In Vitro Demonstration of Human Lipoyl Synthase Catalytic Activity in the Presence of NFU1
Douglas M. Warui, Debangsu Sil, Kyunghoon Lee, Syam Sundar Neti, Olga Esakova, Hayley Knox, Carsten Krebs, Squire J. Booker
Abstract
, has no direct effect on Fe-S cluster transfer from NFU1 or GLRX5 to LIAS. Further, we show that ISCA1 and ISCA2 can enhance LIAS turnover, but only slightly.
Topics & Concepts
In vitroATP synthaseChemistryCatalysisBiochemistryEnzymeBiochemical Acid Research StudiesBiochemical and Molecular ResearchCoenzyme Q10 studies and effects