Photo-induced difluoroalkylation/cyclization of alkyne ketones: a novel strategy to access difluoroalkyl thiofavones
Shengjie Song, Can Luo, Guan Wang, Jingjing Guo, Zhihang Chen, Jianjun Li
Abstract
Br bond homolysis process may also be involved for this transformation. Varieties of difluoroalkyl-substituted thiofavones can be smoothly assembled in moderate to good yields under photocatalyst-, metal- and oxidant-free conditions, thus offering potential applications for pharmaceutical research.
Topics & Concepts
AlkyneChemistryCombinatorial chemistryOrganic chemistryCatalysisFluorine in Organic ChemistrySulfur-Based Synthesis TechniquesRadical Photochemical Reactions