Litcius/Paper detail

The crucial role of silver(<scp>i</scp>)-salts as additives in C–H activation reactions: overall analysis of their versatility and applicability

Renato L. Carvalho, Emilay B. T. Diogo, Simon L. Homölle, Suman Dana, Eufrânio N. da Silva Júnior, Lutz Ackermann

2023Chemical Society Reviews61 citationsDOIOpen Access PDF

Abstract

generation of catalytically active species. This strategy varies according to the type of additive and the nature of the pre-catalyst that is being used. Thus, silver(I)-salts have proven to play an important role, due to the resulting high reactivity derived from the pre-catalysts of the main transition metals used so far. While being powerful and versatile, the use of silver-based additives can raise concerns, since superstoichiometric amounts of silver(I)-salts are typically required. Therefore, it is crucial to first understand the role of silver(I) salts as additives, in order to wisely overcome this barrier and shift towards silver-free systems.

Topics & Concepts

CatalysisTransition metalChemistryCombinatorial chemistryNanotechnologyOrganic chemistryMaterials scienceCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and CatalysisSynthesis and Catalytic Reactions