Conducting Composite Material Based on Chitosan and Single-Wall Carbon Nanotubes for Cellular Technologies
V. V. Kodolova-Chukhontseva, M. A. Shishov, Konstantin Kolbe, Н. В. Смирнова, I. P. Dobrovol’skaya, E. N. Dresvyanina, С. Г. Быстров, N. S. Terebova, Almaz Kamalov, A. É. Bursian, Е. М. Иванькова, V. E. Yudin
Abstract
Biocompatible electrically conducting chitosan-based films filled with single-wall carbon nanotubes were obtained. Atomic force microscopic studies of the free surface topography revealed a change in the morphology of chitosan films filled with single-wall carbon nanotubes. Introducing 0.5 wt.% of single-wall carbon nanotubes into chitosan results in an increase in tensile strength of the films (up to ~180 MPa); the tensile strain values also rise up to ~60%. It was demonstrated that chitosan films containing 0.1–3.0 wt.% of single-wall carbon nanotubes have higher conductivity (10 S/m) than pure chitosan films (10−11 S/m). The investigation of electrical stimulation of human dermal fibroblasts on chitosan/single-wall carbon nanotubes film scaffolds showed that the biological effect of cell electrical stimulation depends on the content of single-walled carbon nanotubes in the chitosan matrix.