Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection
Lei Li, Yoshikazu Honda‐Okubo, Ying Huang, Hyesun Jang, Michael A. Carlock, Jeremy Baldwin, Sakshi Piplani, Anne G. Bebin-Blackwell, David Forgacs, Kaori Sakamoto, Alberto Ospina Stella, Stuart Turville, Tim Chataway, Alex D. Colella, Jamie Triccas, Ted M. Ross, Nikolai Petrovsky
Topics & Concepts
ImmunogenicityVirologyAdjuvantBiologyRecombinant DNAVirusAntibodySpike ProteinImmunityImmune systemImmunologyMedicineGeneCoronavirus disease 2019 (COVID-19)GeneticsInfectious disease (medical specialty)DiseasePathologySARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesTransgenic Plants and Applications