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Direct Detection of Hydrogen Bonds in Supramolecular Systems Using <sup>1</sup> H– <sup>15</sup> N Heteronuclear Multiple Quantum Coherence Spectroscopy

Michael A. Jinks, Mark J. Howard, Federica Rizzi, Stephen M. Goldup, Andrew D. Burnett, Andrew J. Wilson

2022Journal of the American Chemical Society16 citationsDOIOpen Access PDF

Abstract

N resonances facilitates direct detection of intra- and intermolecular hydrogen bonds in mechanically interlocked structures and quadruply hydrogen-bonded dimers─of dialkylaminoureidopyrimidinones, ureidopyrimidinones, and diamidonaphthyridines─in single or multicomponent mixtures to establish tautomeric configuration, conformation, and, to resolve self-sorted speciation.

Topics & Concepts

ChemistryHeteronuclear moleculeSupramolecular chemistryHydrogen bondIntermolecular forceNuclear magnetic resonance spectroscopyTautomerSpectroscopyNuclear Overhauser effectTwo-dimensional nuclear magnetic resonance spectroscopyCrystallographyMoleculeStereochemistryCrystal structureOrganic chemistryPhysicsQuantum mechanicsAdvanced NMR Techniques and ApplicationsCrystallography and molecular interactionsMolecular spectroscopy and chirality
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