Epigenetic therapy in combination with a multi-epitope cancer vaccine targeting shared tumor antigens for high-risk myelodysplastic syndrome - a phase I clinical trial
Staffan Holmberg-Thydén, Inge Høgh Dufva, Anne Ortved Gang, Marie Fredslund Breinholt, Lone Schejbel, Mette Klarskov Andersen, Mohammad Kadivar, Inge Marie Svane, Kirsten Grønbæk, Sine Reker Hadrup, Daniel El Fassi
Topics & Concepts
AzacitidineMedicineMyelodysplastic syndromesAntigenHypomethylating agentELISPOTImmunotherapyEpigenetic therapyImmunologyClinical trialDecitabineOncologyInternal medicineImmune systemBone marrowBiologyDNA methylationCD8Gene expressionBiochemistryGeneAcute Myeloid Leukemia ResearchImmune cells in cancerImmunotherapy and Immune Responses