Recent Advances in Senolysis for Age-Related Diseases
Sae Aratani, Makoto Nakanishi
Abstract
Cellular senescence plays a central role in aging and geriatric diseases. Senolysis is a promising new strategy that selectively kills and eliminates senescent cells to control aging. To date, various senolytic drugs have been discovered and shown efficacy. This review highlights how we can benefit from senolysis.
Topics & Concepts
Cellular senescenceSenescenceCellular AgingBiologyMedicineCell biologyTelomereGeneticsDNAGenePhenotypeTelomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model OrganismsSkin Protection and Aging