LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection
Zeger Debyser, Anne Bruggemans, Siska Van Belle, Julie Janssens, Frauke Christ
Topics & Concepts
IntegraseBiologyChromatinComputational biologySmall moleculeEpigeneticsIntegrase inhibitorHuman immunodeficiency virus (HIV)Transcription factorVirologyCell biologyGeneticsAntiretroviral therapyDNAGeneViral loadHIV Research and TreatmentHIV/AIDS drug development and treatmentBiochemical and Molecular Research