Reduction in intestinal colonization and invasion of internal organs after challenge by homologous and heterologous serovars of <i>Salmonella enterica</i> following vaccination of chickens with a novel trivalent inactivated <i>Salmonella</i> vaccine
Colin Crouch, Chris Pugh, Amit Patel, H G van den Brink, Chris Wharmby, Anna Watts, M.C.W. van Hulten, Stefan P. W. de Vries
Abstract
chicken vaccine was developed and tested. Vaccine induced marked systemic antibody response against all vaccine antigens. Significant reductions in intestinal tract colonization and internal organ invasion. Vaccine efficacy demonstrated against homologous and heterologous serovars.
Topics & Concepts
SerotypeSalmonella entericaHeterologousMicrobiologyBiologySalmonellaVirologyVaccinationInactivated vaccineSalmonella enteritidisColonizationBacteriaGeneGeneticsBiochemistrySalmonella and Campylobacter epidemiologyViral gastroenteritis research and epidemiologyEscherichia coli research studies