Coronavirus Disease 2019 Coagulopathy: Disseminated Intravascular Coagulation and Thrombotic Microangiopathy—Either, Neither, or Both
Marcel Levi, Jecko Thachil
Abstract
Patients with severe coronavirus disease 2019 (COVID-19) infections manifest coagulation abnormalities that have been associated with respiratory deterioration and death.[1] [2] In addition, many patients with severe COVID-19 infections develop venous thromboembolism, which seems to be related to the coagulopathy.[3] It has also been suggested that undiagnosed pulmonary embolism contributes to a sudden deterioration of pulmonary oxygen exchange that is sometimes seen in patients with COVID-19 infections.[4] [5]
Topics & Concepts
CoagulopathyMedicineThrombotic microangiopathyPulmonary embolismDisseminated intravascular coagulationConsumptive CoagulopathyCoronavirus disease 2019 (COVID-19)CoronavirusDiseaseCoagulationRespiratory diseaseIntensive care medicineInternal medicineInfectious disease (medical specialty)LungCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19Sepsis Diagnosis and Treatment