A new paper-based biosensor for therapeutic drug monitoring
Darlin Lantigua, Jamie Trimper, Barış Ünal, Gulden Camci‐Unal
Abstract
Tacrolimus is one of the most effective and prevalent drugs used to combat vascularized composite allotransplantation rejection. We have fabricated a rapid and easy-to-use six-layer paper based microfluidic device using the principles of competitive immunoassays and vertical flow microfluidics for colorimetric detection of tacrolimus in a small volume of blood.
Topics & Concepts
TacrolimusMicrofluidicsAllotransplantationBiosensorNanotechnologyTherapeutic drug monitoringDrugBiomedical engineeringMaterials sciencePharmacologyMedicineTransplantationSurgeryAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionOrgan and Tissue Transplantation Research