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Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents

Duong Tien Anh, Hai Pham‐The, Đỗ Thị Mai Dung, Phan Thị Phương Dung, Huong Le‐Thi‐Thu, Eun Jae Park, Hye Won Jun, Jong Soon Kang, Joo‐Hee Kwon, Trương Thanh Tùng, Sang‐Bae Han, Nguyen‐Hai Nam

2020Bioorganic & Medicinal Chemistry Letters24 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryHistone deacetylaseIndirubinStereochemistryHistone deacetylase inhibitorChemical synthesisHistonePharmacologyCombinatorial chemistryBiochemistryIn vitroVisual artsIndigoMedicineArtGeneHistone Deacetylase Inhibitors ResearchQuinazolinone synthesis and applicationsClick Chemistry and Applications
Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents | Litcius