Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices
Claudio Parolo, Andrea Idili, Jason Heikenfeld, Kevin W. Plaxco
Abstract
, that are independent of the reactive or optical properties of their targets), sensing strategies relying on binding-induced conformational change of bioreceptors are most likely to succeed in such applications.
Topics & Concepts
Computer scienceAnalyticsLab-on-a-chipNanotechnologyData scienceChipBench to bedsideField (mathematics)MicrofluidicsEmbedded systemTelecommunicationsMedical physicsMaterials sciencePure mathematicsMathematicsPhysicsAnalytical Chemistry and SensorsElectrochemical sensors and biosensorsAdvanced biosensing and bioanalysis techniques