A three-dimensional BODIPY–iron(<scp>iii</scp>) compound with improved H<sub>2</sub>O<sub>2</sub>-response for NIR-II photoacoustic imaging guided chemodynamic/photothermal therapy
Changjin Ou, Yewei Zhang, Wei Ge, Liping Zhong, Yong Huang, Weili Si, Wenjun Wang, Yongxiang Zhao, Xiaochen Dong
Abstract
3D boron dipyrromethene (BODIPY)-Fe(iii) coordination polymer nanoparticles can extend absorption to 1300 nm for enhanced ligand-to-metal transfer. The nanoparticles show good cytotoxic hydroxyl radical (˙OH) generation ability, high photothermal conversion, and outstanding NIR-II photoacoustic imaging, displaying synergistic chemodynamic/photothermal therapy.
Topics & Concepts
Photothermal therapyBODIPYPhotoacoustic imaging in biomedicineAbsorption (acoustics)NanoparticleBoronChemistryNuclear chemistryNanotechnologyMaterials scienceFluorescenceOpticsOrganic chemistryPhysicsComposite materialNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisPhotoacoustic and Ultrasonic Imaging