<sup>68</sup>Ga-PSMA PET/CT for the evaluation of metastasis in patients with prostate cancer: A systematic review and meta-analysis.
Jing Zhou, Renhui Wu, Wenrong Wang, Yigang Zhao, Xiaohua Liu
Abstract
OBJECTIVE: Ga-PSMA) positron emission tomography/computed tomography (PET/CT) in detecting metastases in prostate cancer (PCa) patients. MATERIALS AND METHODS: Ga-PSMA PET/CT were selected for qualitative and quantitative analysis. RESULTS: , DOR, and AUC of bone metastases were 0.97, 1.00, 1100.1, 0.03, 37490 and 0.98, respectively. CONCLUSION: Gallium-68-PSMA PET/CT demonstrated outstanding diagnostic performance for bone metastases in PCa patients. The majority of lymph node metastases, lung metastases, and liver metastases overexpressed PSMA, which could be directly detected. However, a considerable number of lesions were false negatives.
Topics & Concepts
MedicineProstate cancerLymph nodeMeta-analysisRadiologyPositron emission tomographyLung cancerPET-CTMetastasisCancerLungNuclear medicineOncologyPathologyInternal medicineProstate Cancer Treatment and ResearchRadiopharmaceutical Chemistry and ApplicationsCancer, Lipids, and Metabolism