Copper(<scp>ii</scp>) complexes containing enoxacin and heterocyclic ligands: synthesis, crystal structures and their biological perspectives
Manish Kumar, Gyanendra Kumar, Dhanraj T. Masram
Abstract
Two copper-based complexes with a distorted square pyramidal geometry show excellent binding and cleavage affinity towards DNA and proteins. Also, these complexes have potential cytotoxicity against MCF-7 cancer cells.
Topics & Concepts
ChemistryCopperCytotoxicitySquare pyramidal molecular geometryDNAStereochemistryCleavage (geology)Combinatorial chemistryEnoxacinCrystallographyBiochemistryIn vitroOrganic chemistryAntibioticsEngineeringGeotechnical engineeringNorfloxacinFracture (geology)CiprofloxacinMetal complexes synthesis and propertiesCrystal structures of chemical compoundsMetal-Organic Frameworks: Synthesis and Applications