New cell-membrane-anchored near-infrared fluorescent probes for viscosity monitoring
Ya Liu, Xiaohua Li, Wen Shi, Huimin Ma
Abstract
= 710 nm) are reported for monitoring viscosity of cell membranes. The probes were found to be selective and sensitive to viscosity, and to quickly (within 2 minutes) and stably anchor onto the cell membrane. Moreover, the applicability of the probe MYN-BS (a superior representative) was demonstrated, revealing a reversible viscosity change with temperature change and an increase in viscosity during cell foaming. The proposed probes may serve as a reliable tool for studying viscosity-related processes of cell membranes.
Topics & Concepts
ViscosityMembraneFluorescenceAmphiphileBiophysicsCellCell membraneInfraredChemical engineeringChemistryMaterials scienceNanotechnologyPolymerCopolymerOrganic chemistryComposite materialBiochemistryOpticsBiologyEngineeringPhysicsLipid Membrane Structure and BehaviorSurfactants and Colloidal SystemsProtein Interaction Studies and Fluorescence Analysis