Targeted delivery of pexidartinib to tumor-associated macrophages via legumain-sensitive dual-coating nanoparticles for cancer immunotherapy
Desheng Liang, Wei-Peng You, Fangfang Zhu, Jiahui Wang, Feng Guo, Jianjun Xu, Xinliang Liu, Haijun Zhong
Topics & Concepts
Tumor microenvironmentCancer immunotherapyIn vivoImmunotherapyChemistryNanomedicineCancer researchDrug deliveryCancerImmune systemCancer cellMelanomaNanoparticleNanotechnologyTumor cellsMaterials scienceMedicineImmunologyInternal medicineBiologyOrganic chemistryBiotechnologyImmune cells in cancerNanoplatforms for cancer theranosticsImmunotherapy and Immune Responses