Ablation of FAS confers allogeneic CD3– CAR T cells with resistance to rejection by T cells and natural killer cells
Silvia Menegatti, Sheila López‐Cobo, Aurélien Sutra Del Galy, Jaime R. Fuentealba, Lisseth Silva, Laëtitia Perrin, Sandrine Heurtebise-Chrétien, Valentine Pottez-Jouatte, Aurélie Darbois, Nina Burgdorf, Anne-Laure Privat, Albane Simon, Marguerite Laprie-Sentenac, Michael Saitakis, Bryce Wick, Beau R. Webber, Branden S. Moriarity, Olivier Lantz, Sebastián Amigorena, Laurie Menger
Topics & Concepts
Natural killer T cellInterleukin 21CD3Chimeric antigen receptorCytotoxic T cellBiologyAntigenImmune systemImmunologyInterleukin 12IL-2 receptorNK-92Antigen-presenting cellCancer researchT cellCD8In vitroBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology