Fabrication of doxorubicin-gated mesoporous polydopamine nanoplatforms for multimode imaging-guided synergistic chemophotothermal therapy of tumors
Min Yang, Ningnan Zhang, Tao Zhang, Xian Yin, Jie Shen
Abstract
. All these positive results certify that the facile incorporation of the antitumor drug gatekeeper and MPDA into one theranostic nanoplatform shows general potential for multimode PA/US imaging and combination chemotherapy/PTT of tumors.
Topics & Concepts
DoxorubicinPhotothermal therapyMaterials scienceNanotechnologyNanocarriersIn vivoDrug deliveryMesoporous organosilicaMesoporous silicaMesoporous materialBiomedical engineeringChemistryChemotherapyMedicineOrganic chemistryBiotechnologySurgeryCatalysisBiologyNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryExtracellular vesicles in disease