Orchestrating AMPK/mTOR signaling to initiate melittin-induced mitophagy: A neuroprotective strategy against Parkinson's disease
Mingran Chen, Xue Wang, Shuangyan Bao, Dexiao Wang, Jie Zhao, Qian Wang, Chaojie Liu, Haiong Zhao, Chenggui Zhang
Topics & Concepts
NeuroprotectionMitophagyPI3K/AKT/mTOR pathwayAMPKParkinson's diseaseMelittinNeurosciencePINK1AutophagySignal transductionChemistryDiseaseCell biologyBiologyMedicinePhosphorylationApoptosisBiochemistryInternal medicineProtein kinase APeptideParkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolism