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First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain

Min-Jeong Kim, Jae‐Hoon Lee, Fernanda Juarez Anaya, Jinsoo Hong, William H. Miller, Sanjay Telu, Prachi Singh, Michelle Cortes, Katharine Henry, George Tye, Michael P. Frankland, Jose A. Montero Santamaria, Jeih-San Liow, Sami S. Zoghbi, Masahiro Fujita, Victor W. Pike, Robert B. Innis

2020European Journal of Nuclear Medicine and Molecular Imaging49 citationsDOIOpen Access PDF

Topics & Concepts

RadioligandCyclooxygenaseMedicineHuman brainRadioligand AssayPharmacologyNuclear medicineInternal medicineChemistryReceptorBiochemistryPsychiatryEnzymeInflammatory mediators and NSAID effectsEstrogen and related hormone effectsEicosanoids and Hypertension Pharmacology
First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain | Litcius