Manganese-Catalyzed [4 + 2] Annulation of N–H Amidines with Vinylene Carbonate via C–H Activation
Yudong Li, Yudong Li, Huan Wang, Ying Li, Ying Li, Yang Li, Yang Li, Yuxia Sun, Chungu Xia, Yuehui Li, Yuehui Li
Abstract
Manganese-catalyzed C-H bond functionalization of aryl amidines for the synthesis of 1-aminoisoquinolines in the presence of vinylene carbonate has been developed. The reaction features a broad substrate scope and proceeds under mild reaction conditions with only the carbonate anion as the byproduct.
Topics & Concepts
AnnulationManganeseCatalysisCarbonateChemistrySubstrate (aquarium)ArylSurface modificationPolymer chemistryOrganic chemistryAlkylOceanographyPhysical chemistryGeologyCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsAsymmetric Hydrogenation and Catalysis