Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians
Minxian Wang, Ramesh Menon, Sanghamitra Mishra, Aniruddh P. Patel, Mark Chaffin, Deepak Tanneeru, Manjari Deshmukh, Oshin Mathew, Sanika Apte, Christina S Devanboo, S. Natarajan Sundaram, Praveena Lakshmipathy, Sakthivel Murugan, Krishna Kumar Sharma, Karthikeyan Rajendran, Sam Santhosh, Rajesh Thachathodiyl, Hisham Ahamed, Aniketh Vijay Balegadde, Thomas Alexander, Krishnan Swaminathan, Rajeev Gupta, Ajit S. Mullasari, Alben Sigamani, Muralidhar Kanchi, Andrew S. Peterson, Adam S. Butterworth, John Danesh, Emanuele Di Angelantonio, Aliya Naheed, Michael Inouye, Rajiv Chowdhury, Vedam L. Ramprasad, Sekar Kathiresan, Ravi Gupta, Amit V. Khera
Topics & Concepts
MedicineCoronary artery diseaseInternal medicineCardiologyDiseasePolygenic risk scoreGeneGeneticsSingle-nucleotide polymorphismGenotypeBiologyGenetic Associations and EpidemiologyBRCA gene mutations in cancerGenomic variations and chromosomal abnormalities