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HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis

Gongshi Bai, Chames Kermi, Henriette Stoy, Carl J. Schiltz, Julien Bacal, Angela M. Zaino, M. Kyle Hadden, Brandt F. Eichman, Massimo Lopes, Karlene A. Cimprich

2020Molecular Cell197 citationsDOIOpen Access PDF

Topics & Concepts

BiologyDNA damageDNA replicationCell biologyGenome instabilityDNA re-replicationPre-replication complexControl of chromosome duplicationGeneticsDNADNA Repair MechanismsMicrotubule and mitosis dynamicsCancer-related Molecular Pathways
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis | Litcius