Fluorescent probes for the detection of chemical warfare agents
Wenqi Meng, Adam C. Sedgwick, Nahyun Kwon, Mingxue Sun, Kai Xiao, Xiao‐Peng He, Eric V. Anslyn, Tony D. James, Juyoung Yoon
Abstract
) to permit in-depth evaluation of their biological interactions and allow potential identification of therapeutic countermeasures. In this review, we provide an overview of the various reported fluorescent probes that have been designed for the detection of CWAs. The mechanism for CWA detection, change in optical output and application for each fluorescent probe are described in detail. The limitations and challenges of currently developed fluorescent probes are discussed providing insight into the future development of this research area. We hope the information provided in this review will give readers a clear understanding of how to design a fluorescent probe for the detection of a specific CWA. We anticipate that this will advance our security systems and provide new tools for environmental and toxicology monitoring.