A review of non-prostanoid, eicosanoid receptors: expression, characterization, regulation, and mechanism of action
Roger G. Biringer
Abstract
Eicosanoid signaling controls a wide range of biological processes from blood pressure homeostasis to inflammation and resolution thereof to the perception of pain and to cell survival itself. Disruption of normal eicosanoid signaling is implicated in numerous disease states. Eicosanoid signaling is facilitated by G-protein-coupled, eicosanoid-specific receptors and the array of associated G-proteins. This review focuses on the expression, characterization, regulation, and mechanism of action of non-prostanoid, eicosanoid receptors.
Topics & Concepts
EicosanoidProstanoidReceptorEicosanoid metabolismInflammationCell biologySignal transductionHomeostasisG protein-coupled receptorMechanism (biology)BiologyImmunologyBiochemistryEnzymeEpistemologyPhilosophyArachidonic acidEicosanoids and Hypertension PharmacologyReceptor Mechanisms and SignalingCardiovascular, Neuropeptides, and Oxidative Stress Research