CISS-Based Label-Free Novel Electrochemical Impedimetric Detection of UVC-Induced DNA Damage
Neeraj Bangruwa, Manish Srivastava, Debabrata Mishra
Abstract
) and the spin selectivity of electrons through DNA was taken into account for the detection of DNA damage for the first time with a limit of detection achieved up to 10 picomolar concentrations of DNA. As the spin-polarized electrons directly probe the structural symmetry, it is robust against perturbation from electronic signals usually found in conventional electrochemical biosensors.
Topics & Concepts
ElectronMaterials scienceDNAAnalytical Chemistry (journal)Detection limitDNA damageChemistryOptoelectronicsMolecular physicsNanotechnologyPhysicsQuantum mechanicsBiochemistryChromatographyAdvanced biosensing and bioanalysis techniquesMolecular Junctions and NanostructuresElectrochemical Analysis and Applications