p53 downregulates PD-L1 expression via miR-34a to inhibit the growth of triple-negative breast cancer cells: a potential clinical immunotherapeutic target
Siyu Deng, Mengna Wang, Chenglong Wang, Yan Zeng, Xue Qin, Yiwen Tan, Bing Liang, Youde Cao
Topics & Concepts
Triple-negative breast cancerCancer researchmicroRNABreast cancerIn vivoPD-L1ImmunotherapyTransfectionDownregulation and upregulationCancerApoptosisBiologyImmune systemChemistryMedicineCell cultureImmunologyInternal medicineBiochemistryGeneticsGeneBiotechnologyMicroRNA in disease regulationCancer Immunotherapy and BiomarkersAdvanced Breast Cancer Therapies