Metal-free synthesis of 1,4-benzodiazepines and quinazolinones from hexafluoroisopropyl 2-aminobenzoates at room temperature
Jiewen Chen, En Liang, Jie Shi, Yinrong Wu, Kangmei Wen, Xingang Yao, Xiaodong Tang
Abstract
A metal-free synthesis of 1,4-benzodiazepines and quinazolinones from hexafluoroisopropyl 2-aminobenzoates has been developed at room temperature.
Topics & Concepts
ChemistryMetalCombinatorial chemistryComputational chemistryOrganic chemistryQuinazolinone synthesis and applicationsSynthesis and Biological EvaluationMulticomponent Synthesis of Heterocycles