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Tuning the electronic transition energy of indole<i>via</i>substitution: application to identify tryptophan-based chromophores that absorb and emit visible light

Robert J. Micikas, Ismail A. Ahmed, Arusha Acharyya, Amos B. Smith, Feng Gai

2021Physical Chemistry Chemical Physics23 citationsDOIOpen Access PDF

Abstract

The unnatural amino acids 4CHO-tryptophan and 4NO<sub>2</sub>-tryptophan can be excited by visible light and could afford useful application as biological chromophores.

Topics & Concepts

Indole testFluorescenceFluorophoreTryptophanPhotochemistryChemistryQuantum yieldChromophoreExcited stateAbsorption (acoustics)Fluorescence spectroscopyMaterials scienceStereochemistryAmino acidOpticsNuclear physicsPhysicsBiochemistryComposite materialAdvanced Fluorescence Microscopy TechniquesPhotoreceptor and optogenetics researchClick Chemistry and Applications