Extracellular targeted protein degradation: an emerging modality for drug discovery
James A. Wells, Kaan Kumru
Topics & Concepts
ExtracellularIntracellularSmall moleculeLysosomeProtein degradationProteasomeDrug discoveryCell biologyProteomeTarget proteinBiologyBiochemistryChemistryEnzymeGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysCAR-T cell therapy research