Dehydroepiandrosterone protects against hepatic glycolipid metabolic disorder and insulin resistance induced by high fat via activation of AMPK-PGC-1α-NRF-1 and IRS1-AKT-GLUT2 signaling pathways
Longlong Li, Yao Yao, Jinlong Zhao, Ji Cao, Haitian Ma
Topics & Concepts
Insulin resistanceEndocrinologyInternal medicineGLUT2AMPKIRS1Insulin receptorProtein kinase BFatty liverDehydroepiandrosteroneInsulinBiologyAMP-activated protein kinaseChemistryProtein kinase ASignal transductionMedicineGlucose transporterKinaseBiochemistryAndrogenDiseaseHormoneHormonal and reproductive studiesDiabetes, Cardiovascular Risks, and LipoproteinsEstrogen and related hormone effects