Pharmacophore screening, molecular docking, ADMET prediction and MD simulations for identification of ALK and MEK potential dual inhibitors
Haoran Zhang, Lichuan Zhang, Chenglong Gao, Rilei Yu, Congmin Kang
Topics & Concepts
ChemistryPharmacophoreDocking (animal)Virtual screeningComputational biologyProtein–ligand dockingIdentification (biology)Combinatorial chemistryStereochemistryBotanyNursingBiologyMedicineLung Cancer Treatments and MutationsCancer therapeutics and mechanismsCancer Mechanisms and Therapy