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Mechanistic Insights into Mitigation of Combined Scaling–Biofouling for a Novel Thin-Film Composite Membrane Based on Incorporated Defensive–Offensive Strategy

Riji Qiu, Junjian Zheng, Xingran Zhang, Fang Li

2025Environmental Science & Technology7 citationsDOI

Abstract

Combined scaling–biofouling is commonly encountered in practical wastewater treatment and desalination due to the coexistence of inorganic scalants and microorganisms, which is a major obstacle limiting the applications of membrane-based technologies. In this study, we developed a simple and effective modification method for the preparation of an anticombined scaling–biofouling thin-film composite (TFC) nanofiltration membrane via a synergetic strategy based on defensive ( i.e., sequestering carboxyl groups) and offensive ( i.e., immobilizing antimicrobial peptides (AMPs)) functions. According to the Extended Derjaguin–Landau–Verwey–Overbeek (XDLVO) analysis, the sequestration of carboxyl groups by AMPs diminishes the acid–base polarity interaction between the biofoulants and membranes, playing a critical role in dismantling the bridge of carboxyl–Ca 2+ –carboxyl and subsequently rendering both scaling ions and carboxyl groups unavailable to fouling. Meanwhile, the immobilization of AMPs on the membranes prevents microbial metabolism and growth by contact-killing mechanisms, endowing the membrane resistance to severe biofouling in the presence of scaling ions. Furthermore, the synergetic effects overcome the permeability–rejection–antifouling trade-off by enhanced water permeance without sacrificing salt rejection. This research provides a novel dimension for developing high-performance TFC membranes for the mitigation of combined scaling–biofouling in the practical application of wastewater treatment and desalination.

Topics & Concepts

BiofoulingMembraneDesalinationFoulingNanofiltrationChemistryChemical engineeringMembrane foulingReverse osmosisThin-film composite membraneEngineeringBiochemistryMembrane Separation TechnologiesGraphene and Nanomaterials ApplicationsAntimicrobial agents and applications