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Successful treatment of refractory prurigo nodularis with abrocitinib

Fang Sun, Z. Wu

2024Clinical Case Reports13 citationsDOIOpen Access PDF

Abstract

Prurigo nodularis is frequently difficult to manage with conventional therapy. Given the pathogenesis and refractory nature, we demonstrate a case in which inhibition of JAK-STAT signaling may significantly improve prurigo nodularis. Based on the results, we would like to draw a conclusion that abrocitinib as an inhibitor of Jak is a promising choice for the treatment of prurigo nodularis.

Topics & Concepts

Prurigo nodularisMedicineRefractory (planetary science)DermatologyPrurigoDupilumabAtopic dermatitisPhysicsAstrobiologyDermatology and Skin DiseasesUrticaria and Related ConditionsContact Dermatitis and Allergies