MiR-21 regulates epithelial–mesenchymal transition in intestinal fibrosis of Crohn's disease by targeting PTEN/mTOR
Zhizhi Wang, Huihui Zhou, Fei Cheng, Zhendong Zhang, Shunhua Long
Topics & Concepts
PTENTIMP1Cancer researchEpithelial–mesenchymal transitionPI3K/AKT/mTOR pathwayFibrosisTissue inhibitor of metalloproteinaseMedicineDownregulation and upregulationMMP9PathologyMatrix metalloproteinaseInternal medicineCancerSignal transductionBiologyMetastasisCell biologyGene expressionBiochemistryGeneInflammatory Bowel DiseaseInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisMicroRNA in disease regulation