Microbial regulators of physiological and reproductive health in women of reproductive age: their local, proximal and distal regulatory roles
Qiuhan Cheng, Siting Lv, Nanlin Yin, Jinfeng Wang
Abstract
The female microbiome is emerging as a key regulator of gynecological and reproductive health. This review summarizes how local and gut microbes affect gynecological outcomes, fertility, and pregnancy through metabolic, immune, and hormonal pathways. We highlight underlying mechanisms and intervention strategies, emphasizing the restoration of microbial homeostasis as a promising avenue for advancing understanding, prevention, and management of women's physiological and reproductive health conditions.
Topics & Concepts
RegulatorBiologyPhysiologyReproductive healthFemale Reproductive TractMicrobiomeReproductive tractPregnancyMedicineReproductive immunologyReproductive medicineReproductive biologyHormoneReproductive physiologyBioinformaticsReproductive technologyInfertilityMaternal healthReproductive successHuman healthReproductive systemReproductionGynecologyPublic healthIntervention (counseling)Affect (linguistics)Reproductive tract infections researchReproductive System and PregnancyGut microbiota and health