Lymph node metastasis: An immunological burden
Amanda W. Lund
Abstract
Lymph node metastasis in breast cancer depends in part on the acquisition of an IFN-dependent, MHC-II+ state that induces regulatory T cell expansion and local immune suppression (Lei et al. 2023. J. Exp. Med.https://doi.org/10.1084/jem.20221847).
Topics & Concepts
Immune systemLymph nodeMetastasisBreast cancerLymph node metastasisMedicineCancer metastasisImmunologyLymphCancerOncologyCancer researchInternal medicinePathologyCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCancer Cells and Metastasis