Ciprofloxacin salts with benzoic acid derivatives: structural aspects, solid-state properties and solubility performance
Artem O. Surov, Nikita A. Vasilev, Alexander P. Voronin, Andrei V. Churakov, Franziska Emmerling, German L. Perlovich
Abstract
In this work, three new pharmaceutical hydrated salts of ciprofloxacin with selected derivatives of benzoic acid were obtained and systematically investigated by several solid-state analytical techniques.
Topics & Concepts
SolubilityBenzoic acidCiprofloxacinSolid-stateChemistryOrganic chemistryCombinatorial chemistryAntibioticsBiochemistryPhysical chemistryCrystallography and molecular interactionsCrystallization and Solubility StudiesAnalytical Chemistry and Chromatography