Systematically investigating the fluorescent signal readout of CRISPR-Cas12a for highly sensitive SARS-CoV-2 detection
Sitong Liu, Tie Xie, Zhaohe Huang, Xiaojing Pei, Shujing Li, Yifan He, Yigang Tong, Guoqi Liu
Topics & Concepts
CRISPRMolecular beaconComputational biologyFörster resonance energy transferSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Cleavage (geology)DNANanotechnologyMolecular diagnosticsCoronavirus disease 2019 (COVID-19)FluorescenceBiologyChemistryGeneticsOligonucleotidePhysicsGeneMaterials scienceMedicineInfectious disease (medical specialty)PaleontologyPathologyFracture (geology)DiseaseQuantum mechanicsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesMosquito-borne diseases and control