Susceptibility Trends of Zoliflodacin against Multidrug-Resistant <i>Neisseria gonorrhoeae</i> Clinical Isolates in Nanjing, China, 2014 to 2018
Wenjing Le, Xiaohong Su, Xiangdi Lou, Xuechun Li, Xiangdong Gong, Baoxi Wang, Caroline A. Genco, John P. Mueller, Peter A. Rice
Abstract
Previously, we reported the potent activity of a novel spiropyrimidinetrione, zoliflodacin, against Neisseria gonorrhoeae isolates collected in 2013 from symptomatic men in Nanjing, China. Here, we investigated trends of susceptibilities to zoliflodacin in 986 isolates collected from men between 2014 and 2018. N. gonorrhoeae isolates were tested for susceptibility to zoliflodacin and seven other antibiotics.
Topics & Concepts
Neisseria gonorrhoeaeMicrobiologyAntibioticsMultiple drug resistanceBiologyNeisseriaceaeChinaGonorrheaMedicineVirologyGeographyHuman immunodeficiency virus (HIV)ArchaeologyReproductive tract infections researchLegume Nitrogen Fixing Symbiosis