A Double-Walled Knotted Cage for Guest-Adaptive Molecular Recognition
Yukari Tamura, Hiroki Takezawa, Makoto Fujita
Abstract
We synthesized a double-walled knotted cage from a flexible tripodal ligand. The characteristic double-walled structure provided a unique adaptive behavior of the cavity upon inclusion of organic molecules, which was evidenced by NMR and X-ray measurements. The semiflexible host framework, restricted by the knotted topology, enabled kinetic molecular recognition revealing the sequential binding of two different guests from their mixture.
Topics & Concepts
ChemistryCageMolecular recognitionMoleculeKinetic energyLigand (biochemistry)Molecular motorCrystallographyChemical physicsTopology (electrical circuits)StereochemistryNanotechnologyReceptorOrganic chemistryClassical mechanicsCombinatoricsPhysicsBiochemistryMaterials scienceMathematicsSupramolecular Chemistry and ComplexesMolecular Sensors and Ion DetectionChemical Synthesis and Analysis