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Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3

Kelvin Y. Chen, Tatsuya Kibayashi, Ambre Giguelay, Mayu Hata, Shunsuke Nakajima, Norihisa Mikami, Yusuke Takeshima, Kenji Ichiyama, Ryusuke Omiya, Leif S. Ludwig, Kunihiro Hattori, Shimon Sakaguchi

2025Nature30 citationsDOIOpen Access PDF

Topics & Concepts

CRISPRGenomeBiologyComputational biologyGenome editingGeneticsHuman genomeCell biologyGeneCRISPR and Genetic EngineeringT-cell and B-cell ImmunologyImmune Cell Function and Interaction
Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3 | Litcius