Litcius/Paper detail

Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV

Heba A. Hofny, Mamdouh F. A. Mohamed, Hesham A. M. Gomaa, Salah A. Abdel‐Aziz, Bahaa G. M. Youssif, Nawal El‐Koussi, Ahmed S. Aboraia

2021Bioorganic Chemistry79 citationsDOI

Topics & Concepts

DNA gyraseNovobiocinTopoisomeraseChemistryTopoisomerase IVTopoisomerase inhibitorQuinolineEscherichia coliAntibacterial activityDNAStereochemistryBiochemistryBacteriaBiologyAntibioticsOrganic chemistryGeneticsGeneCancer therapeutics and mechanismsSynthesis and biological activitySynthesis and Biological Evaluation