Dystrophin Restoration after Adeno-Associated Virus U7–Mediated Dmd Exon Skipping Is Modulated by Muscular Exercise in the Severe D2-Mdx Duchenne Muscular Dystrophy Murine Model
Alexandra Monceau, Dylan Moutachi, Mégane Lemaître, Luis Garcı́a, Capucine Trollet, Denis Furling, Arnaud F. Klein, Arnaud Ferry
Topics & Concepts
DystrophinDuchenne muscular dystrophyExon skippingmdx mouseMuscular dystrophySkeletal muscleUtrophinMedicineAdeno-associated virusGenetic enhancementExonInternal medicineEndocrinologyBiologyGeneGeneticsAlternative splicingRecombinant DNAVector (molecular biology)Muscle Physiology and DisordersVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects