Oleanolic acid administration alleviates neuropathic pain after a peripheral nerve injury by regulating microglia polarization-mediated neuroinflammation
Xuyang Li, Guangzhi Wu, Miyang Li, Zhan Zhang
Abstract
Neuropathic pain caused by a peripheral nerve injury constitutes a great challenge in clinical treatments due to the unsatisfactory efficacy of the current strategy.
Topics & Concepts
Oleanolic acidMicrogliaNeuroinflammationPharmacologyTLR4Neuropathic painChemistryMedicineInflammationImmunologyPathologyAlternative medicinePharmacological Effects of Natural CompoundsPain Mechanisms and TreatmentsNatural product bioactivities and synthesis