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Acute cadmium exposure induces GSDME-mediated pyroptosis in triple-negative breast cancer cells through ROS generation and NLRP3 inflammasome pathway activation

Jie Tang, Mingrong Bei, Jia Zhu, Guangtao Xu, Deqing Chen, Xin Jin, Jianzhong Huang, Jingjian Dong, Lili Shi, Long Xu, Bo Hu

2021Environmental Toxicology and Pharmacology75 citationsDOI

Topics & Concepts

Triple-negative breast cancerPyroptosisCancer researchChemistryViability assayInflammasomeApoptosisDNA damageCaspase 1Cyclin-dependent kinase 1Cyclin B1Programmed cell deathCell cycleBreast cancerBiologyCancerInternal medicineMedicineBiochemistryReceptorDNAInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideBiomarkers in Disease Mechanisms
Acute cadmium exposure induces GSDME-mediated pyroptosis in triple-negative breast cancer cells through ROS generation and NLRP3 inflammasome pathway activation | Litcius