Many small steps towards a COVID-19 drug
Daniel A. Erlanson
Abstract
A large-scale screening campaign has yielded dozens of crystal structures of small molecule fragments that bind to the main protease of SARS-CoV-2. The global research community is encouraged to pursue these as drug discovery starting points for COVID-19.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakDrug discoveryDrugSars virusSmall moleculeVirologyComputational biologyDrug repositioningBetacoronavirusData scienceMedicineComputer scienceBiologyBioinformaticsPharmacologyInfectious disease (medical specialty)GeneticsPathologyDiseaseOutbreakComputational Drug Discovery MethodsSynthesis and biological activitySARS-CoV-2 and COVID-19 Research